STRINGSTRING
nnrD protein (Streptococcus pneumoniae R6) - STRING interaction network
"nnrD" - ADP-dependent in Streptococcus pneumoniae R6
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
nnrDADP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (290 aa)    
Predicted Functional Partners:
folD
Bifunctional protein FolD; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (306 aa)
              0.682
spr1590
Uncharacterized protein; Similar to isochorismatase (166 aa)
     
        0.588
entB
Isochorismatase (191 aa)
     
        0.588
celB
Competence induced; comE-like protein B; Putative DNA uptake by homology (746 aa)
   
   
  0.479
spr1760
annotation not available (172 aa)
   
        0.469
spr1318
Uncharacterized protein; Putative acetyltransferase (164 aa)
   
        0.469
spr0733
annotation not available (136 aa)
              0.452
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose (424 aa)
              0.452
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate (246 aa)
              0.452
purL
annotation not available (1242 aa)
              0.450
Your Current Organism:
Streptococcus pneumoniae R6
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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