coaA protein (Streptococcus pneumoniae) - STRING interaction network

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Score

coaA

Pantothenate kinase. (316 aa)

Predicted Functional Partners:

kdtB

0.967

dfp

0.919

dfp-2

0.916

dgkA

0.730

fni

0.722

rpsT

0.713

aroD

0.642

coaE

0.640

flaR

0.590

spr0742

0.523

Your Current Organism:

Streptococcus pneumoniae

NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
aroD	coaA	spr1235	spr0741	3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.	Pantothenate kinase.	0.642
aroD	dgkA	spr1235	spr0870	3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.	Diacylglycerol kinase.	0.597
aroD	fni	spr1235	spr0341	3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.	Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).	0.535
coaA	aroD	spr0741	spr1235	Pantothenate kinase.	3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.	0.642
coaA	coaE	spr0741	spr0873	Pantothenate kinase.	Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	0.640
coaA	dfp	spr0741	spr1110	Pantothenate kinase.	Similar to C-terminal region of the Dfp protein.	0.919
coaA	dfp-2	spr0741	spr1111	Pantothenate kinase.	Similar to N-terminal region of the Dfp protein.	0.916
coaA	dgkA	spr0741	spr0870	Pantothenate kinase.	Diacylglycerol kinase.	0.730
coaA	flaR	spr0741	spr0739	Pantothenate kinase.	Modulates DNA topology.	0.590
coaA	fni	spr0741	spr0341	Pantothenate kinase.	Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).	0.722
coaA	kdtB	spr0741	spr1783	Pantothenate kinase.	Lipopolysaccharide core biosynthesis protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.	0.967
coaA	rpsT	spr0741	spr0740	Pantothenate kinase.	30S Ribosomal protein subunit S20; Binds directly to 16S ribosomal RNA.	0.713
coaA	spr0742	spr0741	spr0742	Pantothenate kinase.	Hypothetical protein.	0.523
coaE	coaA	spr0873	spr0741	Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Pantothenate kinase.	0.640
coaE	dfp	spr0873	spr1110	Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Similar to C-terminal region of the Dfp protein.	0.576
coaE	dfp-2	spr0873	spr1111	Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Similar to N-terminal region of the Dfp protein.	0.635
coaE	dgkA	spr0873	spr0870	Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Diacylglycerol kinase.	0.641
coaE	kdtB	spr0873	spr1783	Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Lipopolysaccharide core biosynthesis protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.	0.996
dfp	coaA	spr1110	spr0741	Similar to C-terminal region of the Dfp protein.	Pantothenate kinase.	0.919
dfp	coaE	spr1110	spr0873	Similar to C-terminal region of the Dfp protein.	Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	0.576

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