Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABC-MSP-8ABC transporter membrane-spanning permease - ribose/galactose transport; Belongs to the binding-protein-dependent transport system permease family. (318 aa)    
Predicted Functional Partners:
ABC-NBD-12
ABC transporter ATP-binding protein - ribose/galactose transport.
 
 0.999
ABC-MSP-7
ABC transporter membrane-spanning permease - ribose/galactose transport; Belongs to the binding-protein-dependent transport system permease family.
 
0.999
spr0747
Conserved hypothetical protein; Similar to basic membrane protein A from Lactococcus lactis subsp. lactis.
 
 
 0.994
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
  
 0.745
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
  
  
 0.731
pdp
Pyrimidine nucleoside phosphorylase.
     
 0.725
spr0743
Conserved hypothetical protein.
  
    0.624
spr0751
Degenerate transposase (orf1).
       0.547
coaA
Pantothenate kinase.
       0.489
rpsT
30S Ribosomal protein subunit S20; Binds directly to 16S ribosomal RNA.
  
    0.476
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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