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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spr0773Conserved hypothetical protein; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (408 aa)    
Predicted Functional Partners:
nifU
NifU protein.
 
 
 0.996
spr0772
Conserved hypothetical protein.
 
 
 0.990
ABC-NBD-13
ABC transporter ATP-binding protein - unknown substrate.
 
  
 0.987
spr0775
Conserved hypothetical protein.
 
 
 0.975
trxB
Thioredoxin reductase.
  
 
 0.916
metB
Cystathionine gamma-synthase.
    
 0.904
spr0669
Hypothetical protein.
    
   0.841
spr0770
Hypothetical protein.
       0.465
dnaX
DNA-directed DNA polymerase III chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
     
 0.439
spr0980
Conserved hypothetical protein.
 
  
 0.433
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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