Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spr0777Conserved hypothetical protein; Putative permease. (369 aa)    
Predicted Functional Partners:
spr1730
Hypothetical protein.
      
 0.890
spr1259
Conserved hypothetical protein.
     
 0.889
ABC-MSP-6
ABC transporter membrane-spanning permease - unknown substrate.
     
 0.887
spr0466
Conserved hypothetical protein, truncation; blpB.
   
  
 0.884
spr2014
Conserved hypothetical protein.
     
 0.883
ABC-NBD-5
ABC transporter ATP-binding protein - unknown substrate.
     
 0.882
dacA
D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
       0.633
spr1260
Conserved hypothetical protein; Similar to E. coli extragenic suppressor protein SuhB.
     
 0.614
spr1403
Hypothetical protein.
     
 0.609
hpf
Conserved hypothetical protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
   
  
 0.599
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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