Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hsdR-2Type 1 restriction modification system endonuclease R. (1116 aa)    
Predicted Functional Partners:
hsdM-2
Type I restriction modification enzyme methylase subunit.
 
 
 0.996
hsdS-4
Type I restriction-modification enzyme 1, S subunit.
 
 
 0.994
hsdM
EcoE type I restriction modification enzyme M subunit.
 
 
 0.979
hsdS
Type I restriction enzyme.
 
 
 0.960
hsdS-3
Type I site-specific deoxyribonuclease chain S.
 
 
 0.958
hsdS-2
Type I restriction enzyme EcoKI specificity protein (S protein).
 
 
 0.955
spr1130
Hypothetical protein; Probable endonuclease.
  
  
 0.900
recA
DNA recombination/repair; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs (By similarity). It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity). Required for DNA transformation; protects transforming DNA from degradation, possibly in combination with DprA. Present at 15,000-30,000 monomers per competent cell.
      
 0.441
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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