Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spr0809Conserved hypothetical protein; Belongs to the SprT family. (149 aa)    
Predicted Functional Partners:
tex
Toxin expression - transcriptional accessory protein.
  
  
 0.869
spr0810
Hypothetical protein.
  
    0.786
lacR
Lactose phosphotransferase system repressor.
      
 0.759
spr0837
Conserved hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family.
  
     0.687
spr0804
Conserved hypothetical protein.
 
     0.654
spr1782
Conserved hypothetical protein.
 
     0.645
spr0805
Conserved hypothetical protein.
 
    0.592
spr0331
Conserved hypothetical protein; Belongs to the UPF0398 family.
  
     0.586
spr0806
Hypothetical protein.
  
    0.548
spr0807
Conserved hypothetical protein.
       0.548
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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