STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
butBeta-alanine synthase or beta-ureidopropionase. (291 aa)    
Predicted Functional Partners:
aguA
Conserved hypothetical protein.
 
 0.999
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
 
 0.983
bltD
Spermine/spermidine acetyltransferase.
    
  0.900
nspC
Carboxynorspermidine decarboxylase.
     
 0.815
spr0820
Conserved hypothetical protein.
  
    0.789
guaA
Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP.
   
 
 0.585
comD
Histidine protein kinase; Required for induction of competence.
      
 0.547
cinA
Competence induced protein A; Belongs to the CinA family.
     
 0.524
purL
Phosphoribosylformylglycinamide synthetase.
  
  
 0.522
gdhA
NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
  
 0.445
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.