Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rpmG50S Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (49 aa)    
Predicted Functional Partners:
rpsI
30S Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.996
rpmF
50S Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
  
 
 0.994
rplW
50S Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
  
 
 0.977
rpsN
30S Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
  
 
 0.972
rpsR
30S Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
  
 
 0.972
rpmJ
50S Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
  
 
 0.968
rpsT
30S Ribosomal protein subunit S20; Binds directly to 16S ribosomal RNA.
   
 
 0.966
rpsF
30S Ribosomal protein S6 (S6); Binds together with S18 to 16S ribosomal RNA.
  
 
 0.964
rplL
50S Ribosomal protein L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
  
 
 0.962
rpsP
30S Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
  
 
 0.961
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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