| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| arcB | gpmB | spr1957 | spr0219 | Ornithine transcarbamoylase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Phosphoglycerate mutase 2 paralog. | 0.429 |
| arcB | gpmB-2 | spr1957 | spr0887 | Ornithine transcarbamoylase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Phosphoglycerate mutase. | 0.429 |
| bglA | gpmB | spr0244 | spr0219 | 6-phospho-beta-glucosidase; Belongs to the glycosyl hydrolase 1 family. | Phosphoglycerate mutase 2 paralog. | 0.431 |
| bglA | gpmB-2 | spr0244 | spr0887 | 6-phospho-beta-glucosidase; Belongs to the glycosyl hydrolase 1 family. | Phosphoglycerate mutase. | 0.431 |
| ebsC | gcaD | spr0888 | spr0891 | Regulatory protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.424 |
| ebsC | gpmB-2 | spr0888 | spr0887 | Regulatory protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | Phosphoglycerate mutase. | 0.801 |
| ebsC | spr0889 | spr0888 | spr0889 | Regulatory protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | Conserved hypothetical protein. | 0.797 |
| ebsC | spr0890 | spr0888 | spr0890 | Regulatory protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | Hypothetical protein. | 0.584 |
| ebsC | spr0892 | spr0888 | spr0892 | Regulatory protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | Conserved hypothetical protein. | 0.431 |
| gcaD | ebsC | spr0891 | spr0888 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Regulatory protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | 0.424 |
| gcaD | gpmB-2 | spr0891 | spr0887 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Phosphoglycerate mutase. | 0.421 |
| gcaD | spr0889 | spr0891 | spr0889 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Conserved hypothetical protein. | 0.425 |
| gcaD | spr0890 | spr0891 | spr0890 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Hypothetical protein. | 0.582 |
| gcaD | spr0892 | spr0891 | spr0892 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Conserved hypothetical protein. | 0.817 |
| gpmA | gpmB | spr1499 | spr0219 | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Phosphoglycerate mutase 2 paralog. | 0.498 |
| gpmA | gpmB-2 | spr1499 | spr0887 | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Phosphoglycerate mutase. | 0.824 |
| gpmA | pykF | spr1499 | spr0797 | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Pyruvate kinase I; fructose-stimulated. | 0.630 |
| gpmB | arcB | spr0219 | spr1957 | Phosphoglycerate mutase 2 paralog. | Ornithine transcarbamoylase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.429 |
| gpmB | bglA | spr0219 | spr0244 | Phosphoglycerate mutase 2 paralog. | 6-phospho-beta-glucosidase; Belongs to the glycosyl hydrolase 1 family. | 0.431 |
| gpmB | gpmA | spr0219 | spr1499 | Phosphoglycerate mutase 2 paralog. | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.498 |