Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
yfnACationic amino acid transporter - APC Superfamily. (467 aa)    
Predicted Functional Partners:
ccdA-2
Cytochrome c-type biogenesis protein.
     
 0.803
phtD
Pneumococcal histidine triad protein D precursor.
     
 0.672
arcC
Carbamate kinase; Belongs to the carbamate kinase family.
  
  
 0.637
arcB
Ornithine transcarbamoylase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
  
 0.578
dexB
Alpha, 1-6-glucosidase.
   
 0.522
nplT
Neopullulanase; Belongs to the glycosyl hydrolase 13 family.
   
 0.522
amy
Alpha-amylase precursor; Belongs to the glycosyl hydrolase 13 family.
   
 0.522
dexS
Dextran glucosidase; Also highly similar to trehalose-6-phosphate hydrolase.
   
 0.522
gtfA
Dextransucrase (sucrose 6-glucosyltransferase).
   
 0.522
adcR
Transcriptional repressor for Zn(2+)-responsive expression.
      
 0.518
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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