Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABC-SBP-6ABC transporter substrate-binding protein - iron transport. (341 aa)    
Predicted Functional Partners:
ABC-NBD-15
ABC transporter ATP-binding protein - iron transport.
 
 0.998
ABC-MSP-9
ABC transporter membrane-spanning permease - iron transport; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 0.997
ABC-MSP-10
ABC transporter membrane-spanning permease - iron transport; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.992
spr1178
Hypothetical protein.
   
  
 0.935
hexA
DNA mismatch repair protein HexA; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step.
      
 0.881
fecE
ABC transporter ATP-binding protein - ferric iron transport.
 
  
 0.599
fatD
ABC transporter membrane-spanning permease - ferric iron transport; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.549
ribA
Riboflavin biosynthesis; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.510
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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