Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spr0963Hypothetical protein. (260 aa)    
Predicted Functional Partners:
spr0962
Conserved hypothetical protein.
  
    0.775
rffD
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
       0.762
spr0967
Conserved hypothetical protein.
 
    0.719
spr0964
Hypothetical protein.
  
    0.705
spr0965
Hypothetical protein.
  
  
 0.650
spr0966
Conserved hypothetical protein; Probable acid-CoA ligase.
  
  
 0.650
nikS
Nikkomycin biosynthesis protein, carboxylase.
  
    0.629
spr0968
Hypothetical protein.
  
    0.617
spr0970
Conserved hypothetical protein; Probable acetyltransferase.
  
    0.559
mutR-2
Similar to positive transcriptional regulator MutR.
     
 0.450
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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