Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
lacG-2Phospho-beta-D-galactosidase; Belongs to the glycosyl hydrolase 1 family. (468 aa)    
Predicted Functional Partners:
lacE
PTS system, lactose-specific IIBC component.
 
 
 0.998
lacF
PTS system, lactose-specific IIA component.
 
 
 0.996
lacB
Galactose-6-phosphate isomerase LacB subunit.
 
 
 0.993
lacA
Galactose-6-phosphate isomerase LacA subunit.
 
 
 0.985
PTS-EII-11
Phosphotransferase system sugar-specific EII component.
 
 
 0.974
lacD
Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family.
 
  
 0.949
lacC
Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
  
  
 0.947
lacT
Antiterminator protein.
  
  
 0.937
PTS-EII-10
Phosphotransferase system sugar-specific EII component.
  
 
 0.908
lacG
Phospho-beta-D-galactosidase; Belongs to the glycosyl hydrolase 1 family.
  
  
0.905
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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