Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
lacBGalactose-6-phosphate isomerase LacB subunit. (171 aa)    
Predicted Functional Partners:
lacC
Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.999
lacA
Galactose-6-phosphate isomerase LacA subunit.
 
 0.999
lacG-2
Phospho-beta-D-galactosidase; Belongs to the glycosyl hydrolase 1 family.
 
 
 0.993
lacD
Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family.
 
  
 0.993
lacG
Phospho-beta-D-galactosidase; Belongs to the glycosyl hydrolase 1 family.
 
 
 0.973
lacE
PTS system, lactose-specific IIBC component.
 
  
 0.938
pfkA
6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 
 0.931
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
  
 0.920
agaS
Tagatose-6-phosphate ketose/aldose isomerase.
   
 
  0.901
spr0580
Conserved hypothetical protein; Belongs to the UPF0340 family.
 
    0.856
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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