STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spr1102Uncharacterized restriction enzyme, interrupted-N. (625 aa)    
Predicted Functional Partners:
spr1101
Uncharacterized restriction enzyme, interrupted-C.
     0.986
spnIM
DNA modification methyltransferase; Belongs to the N(4)/N(6)-methyltransferase family.
     
 0.952
tmcAL
Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
      
 0.868
spr1103
Hypothetical protein.
       0.593
spr1104
Hypothetical protein.
       0.578
hsdM
EcoE type I restriction modification enzyme M subunit.
  
 
 0.519
vicX
VicX protein.
       0.512
hk02
Histidine kinase.
       0.512
rr02
Response regulator.
       0.512
mutY
Similar to A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
       0.512
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.