STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
amyAlpha-amylase precursor; Belongs to the glycosyl hydrolase 13 family. (484 aa)    
Predicted Functional Partners:
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
  
 
 0.971
pulI
Thermostable pullulanase; Belongs to the glycosyl hydrolase 13 family.
 
 
 0.943
malP
Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 0.928
malM
4-alpha-glucanotransferase (amylomaltase); Belongs to the disproportionating enzyme family.
  
 
 0.919
spr0669
Hypothetical protein.
  
 
 0.909
nplT
Neopullulanase; Belongs to the glycosyl hydrolase 13 family.
 
 
0.909
glgA
Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
  
  
 0.738
malD
ABC transporter membrane-spanning permease - maltose/maltodextrin; Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the substrate across the membrane.
  
  
 0.666
yfnA
Cationic amino acid transporter - APC Superfamily.
   
 0.651
PTS-EII-12
Phosphotransferase system sugar-specific EII component.
  
  
 0.648
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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