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tpi protein (Streptococcus pneumoniae R6) - STRING interaction network
"tpi" - Triosephosphate isomerase in Streptococcus pneumoniae R6
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
tpiTriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family (259 aa)    
Predicted Functional Partners:
pgk
annotation not available (398 aa)
 
  0.999
gapA
annotation not available (359 aa)
  0.998
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (293 aa)
   
 
  0.992
gpi
annotation not available (449 aa)
   
  0.991
eno
Enolase; Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (434 aa)
 
 
  0.975
pfkA
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (335 aa)
 
 
  0.966
gapN
annotation not available (474 aa)
   
  0.953
tktA
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (658 aa)
 
  0.945
pykF
annotation not available (501 aa)
 
   
  0.937
fucA
annotation not available (217 aa)
       
  0.917
Your Current Organism:
Streptococcus pneumoniae R6
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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