Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| adcB | psaA | spr1976 | spr1494 | ABC transporter membrane-spanning permease - Zinc (Zn2+) transport. | ABC transporter substrate-binding protein - manganese transport; Part of an ATP-driven transport system; Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily. | 0.927 |
| adcB | psaB | spr1976 | spr1492 | ABC transporter membrane-spanning permease - Zinc (Zn2+) transport. | ABC transporter ATP-binding protein - manganese transport. | 0.906 |
| adcB | psaC | spr1976 | spr1493 | ABC transporter membrane-spanning permease - Zinc (Zn2+) transport. | ABC transporter membrane-spanning permease - manganese transport. | 0.520 |
| flpA | lytA | spr0868 | spr1754 | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | Autolysin (N-acetylmuramoyl-L-alanine amidase). | 0.911 |
| flpA | ply | spr0868 | spr1739 | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | Pneumolysin (sulfhydryl-activated toxin that lyses cholesterol containing membranes); Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity). | 0.951 |
| flpA | ppmA | spr0868 | spr0884 | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | Proteinase maturation protein; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. | 0.508 |
| flpA | psaA | spr0868 | spr1494 | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | ABC transporter substrate-binding protein - manganese transport; Part of an ATP-driven transport system; Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily. | 0.925 |
| flpA | pspA | spr0868 | spr0121 | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | Surface protein pspA precursor. | 0.797 |
| flpA | pspC | spr0868 | spr1995 | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | Choline binding protein A. | 0.887 |
| lytA | flpA | spr1754 | spr0868 | Autolysin (N-acetylmuramoyl-L-alanine amidase). | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | 0.911 |
| lytA | ply | spr1754 | spr1739 | Autolysin (N-acetylmuramoyl-L-alanine amidase). | Pneumolysin (sulfhydryl-activated toxin that lyses cholesterol containing membranes); Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity). | 0.949 |
| lytA | prtA | spr1754 | spr0561 | Autolysin (N-acetylmuramoyl-L-alanine amidase). | Cell wall-associated serine proteinase precursor PrtA. | 0.420 |
| lytA | psaA | spr1754 | spr1494 | Autolysin (N-acetylmuramoyl-L-alanine amidase). | ABC transporter substrate-binding protein - manganese transport; Part of an ATP-driven transport system; Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily. | 0.949 |
| lytA | pspA | spr1754 | spr0121 | Autolysin (N-acetylmuramoyl-L-alanine amidase). | Surface protein pspA precursor. | 0.518 |
| lytA | pspC | spr1754 | spr1995 | Autolysin (N-acetylmuramoyl-L-alanine amidase). | Choline binding protein A. | 0.542 |
| ply | flpA | spr1739 | spr0868 | Pneumolysin (sulfhydryl-activated toxin that lyses cholesterol containing membranes); Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity). | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | 0.951 |
| ply | lytA | spr1739 | spr1754 | Pneumolysin (sulfhydryl-activated toxin that lyses cholesterol containing membranes); Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity). | Autolysin (N-acetylmuramoyl-L-alanine amidase). | 0.949 |
| ply | ppmA | spr1739 | spr0884 | Pneumolysin (sulfhydryl-activated toxin that lyses cholesterol containing membranes); Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity). | Proteinase maturation protein; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. | 0.648 |
| ply | prtA | spr1739 | spr0561 | Pneumolysin (sulfhydryl-activated toxin that lyses cholesterol containing membranes); Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity). | Cell wall-associated serine proteinase precursor PrtA. | 0.556 |
| ply | psaA | spr1739 | spr1494 | Pneumolysin (sulfhydryl-activated toxin that lyses cholesterol containing membranes); Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity). | ABC transporter substrate-binding protein - manganese transport; Part of an ATP-driven transport system; Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily. | 0.967 |
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