| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aqpZ | dnaJ | spr1604 | spr0456 | Aquaporin Z - water channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Heat-shock protein (activation of DnaK); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | 0.580 |
| aqpZ | dnaK | spr1604 | spr0455 | Aquaporin Z - water channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Class I heat-shock protein (molecular chaperone); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.599 |
| aqpZ | glpK | spr1604 | spr1991 | Aquaporin Z - water channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.673 |
| aqpZ | ndk | spr1604 | spr1775 | Aquaporin Z - water channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.585 |
| aqpZ | spr1356 | spr1604 | spr1356 | Aquaporin Z - water channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Conserved hypothetical protein. | 0.535 |
| aqpZ | spr1605 | spr1604 | spr1605 | Aquaporin Z - water channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Hypothetical protein. | 0.560 |
| aqpZ | spr1838 | spr1604 | spr1838 | Aquaporin Z - water channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Hypothetical protein. | 0.535 |
| aqpZ | spr1989 | spr1604 | spr1989 | Aquaporin Z - water channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol-3-phosphate dehydrogenase, truncation. | 0.520 |
| aqpZ | spr1990 | spr1604 | spr1990 | Aquaporin Z - water channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol-3-phosphate dehydrogenase, truncation. | 0.520 |
| aqpZ | tehB | spr1604 | spr0880 | Aquaporin Z - water channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Tellurite resistance. | 0.933 |
| dnaJ | aqpZ | spr0456 | spr1604 | Heat-shock protein (activation of DnaK); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | Aquaporin Z - water channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.580 |
| dnaJ | dnaK | spr0456 | spr0455 | Heat-shock protein (activation of DnaK); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | Class I heat-shock protein (molecular chaperone); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
| dnaJ | ndk | spr0456 | spr1775 | Heat-shock protein (activation of DnaK); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.773 |
| dnaJ | spr1356 | spr0456 | spr1356 | Heat-shock protein (activation of DnaK); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | Conserved hypothetical protein. | 0.884 |
| dnaJ | spr1838 | spr0456 | spr1838 | Heat-shock protein (activation of DnaK); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | Hypothetical protein. | 0.723 |
| dnaK | aqpZ | spr0455 | spr1604 | Class I heat-shock protein (molecular chaperone); Acts as a chaperone; Belongs to the heat shock protein 70 family. | Aquaporin Z - water channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.599 |
| dnaK | dnaJ | spr0455 | spr0456 | Class I heat-shock protein (molecular chaperone); Acts as a chaperone; Belongs to the heat shock protein 70 family. | Heat-shock protein (activation of DnaK); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | 0.999 |
| dnaK | glpK | spr0455 | spr1991 | Class I heat-shock protein (molecular chaperone); Acts as a chaperone; Belongs to the heat shock protein 70 family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.586 |
| dnaK | ndk | spr0455 | spr1775 | Class I heat-shock protein (molecular chaperone); Acts as a chaperone; Belongs to the heat shock protein 70 family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.554 |
| dnaK | spr1356 | spr0455 | spr1356 | Class I heat-shock protein (molecular chaperone); Acts as a chaperone; Belongs to the heat shock protein 70 family. | Conserved hypothetical protein. | 0.847 |
