Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABC-SBP-11ABC transporter substrate-binding protein - unknown substrate. (355 aa)    
Predicted Functional Partners:
ABC-MSP-20
ABC transporter membrane-spanning permease - unknown substrate.
 
 
 0.986
ABC-NBD-26
ABC transporter ATP-binding protein - unknown substrate; Belongs to the ABC transporter superfamily.
 
 
 0.956
ABC-MSP-5
ABC transporter membrane-spanning permease - iron transport.
 
 
 0.949
ABC-MSP-4
ABC transporter membrane-spanning permease - iron transport.
 
 
 0.945
spr0091
Conserved hypothetical protein; Putative sugar transferase related protein.
  
   
 0.902
spr1655
Conserved hypothetical protein; Putative glycosyltransferase.
      
 0.885
ABC-NBD-3
ABC transporter ATP-binding protein - iron transport; Belongs to the ABC transporter superfamily.
 
 
 0.869
capD
CapD protein, required for the biosynthesis of type 1 capsular polysaccharide.
      
 0.738
spr1646
Hypothetical protein.
       0.709
tarJ
Conserved hypothetical protein; Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate.
  
   
 0.662
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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