Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
spr1649Conserved hypothetical protein; Putative transcriptional regulator (phoU like). (213 aa)    
Predicted Functional Partners:
galE-2
UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
    0.844
galT
Galactose-1-phosphate uridylyltransferase.
       0.757
pstA
ABC transporter membrane-spanning permease - phosphate transport.
 
  
 0.709
phoU-2
Negative regulator of pho regulon for phosphate transport; Plays a role in the regulation of phosphate uptake.
  
     0.693
pstB-2
ABC transporter ATP-binding protein - phosphate transport; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
  
 0.662
spr1650
Hypothetical protein.
  
    0.661
pstB
ABC transporter ATP-binding protein - phosphate transport; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
  
 0.645
pstA-2
ABC transporter membrane-spanning permease - phosphate transport.
 
  
 0.624
pstB-3
ABC transporter ATP-binding protein - phosphate transport; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
  
 0.619
spr1651
Hypothetical protein.
  
    0.586
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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