Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spr1655Conserved hypothetical protein; Putative glycosyltransferase. (243 aa)    
Predicted Functional Partners:
spr1654
Conserved hypothetical protein; Putative role in biosynthesis of amino sugar; Belongs to the DegT/DnrJ/EryC1 family.
 
 0.999
spr0091
Conserved hypothetical protein; Putative sugar transferase related protein.
  
 0.997
capD
CapD protein, required for the biosynthesis of type 1 capsular polysaccharide.
 
  
 0.992
epsG
Glycosyltransferase involved exopolysaccharide (EPS) synthesis.
 
  
 0.942
spr0136
Glycosyl transferase, family 2.
 
  
 0.935
spr1224
Conserved hypothetical protein; Similar to capsular polysaccharide biosynthsis protein.
 
  
 0.928
bacA
A lipid kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
 
  
 0.920
ABC-SBP-11
ABC transporter substrate-binding protein - unknown substrate.
      
 0.885
cps23FU
Galactosyl transferase paralog.
 
  
 0.810
spr1150
Conserved hypothetical protein; Probable oligosaccharide repeat unit transporter.
 
  
 0.735
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.