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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spr1658Conserved hypothetical protein. (176 aa)    
Predicted Functional Partners:
spr1659
Hypothetical protein.
  
    0.815
ABC-N/P-5
ABC transporter ATP-binding/membrane spanning protein - unknown substrate.
  
    0.565
ABC-N/P-6
ABC transporter ATP-binding/membrane spanning protein - unknown substrate.
       0.560
hk13
Histidine kinase.
  
    0.537
spr0168
Conserved hypothetical protein; MccF-like proteins.
  
    0.469
exoA
Exodeoxyribonuclease; In addition to 3'- to 5'-exonuclease and 3'-phosphatase activities, ExoA was shown to make single-strand breaks at apurinic sites in DNA; Belongs to the DNA repair enzymes AP/ExoA family.
  
    0.455
spr1611
Hypothetical protein.
   
    0.436
spr0144
Conserved hypothetical protein.
  
     0.419
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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