Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
galRGalR, member of GalR-LacI family of transcriptional regulators, binds DNA; regulator of gal operon. (335 aa)    
Predicted Functional Partners:
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
  
 0.991
scrR-2
Sucrose operon repressor (SCR operon regulatory protein).
  
  
 0.934
malR
Maltose operon transcriptional repressor; Transcriptional repressor of the maltosaccharide utilization operons malxCD and malMP.
  
   
 0.902
regR
Transcription regulator, member of GalR family.
  
   
 0.898
galT-2
Galactose-1-phosphate uridylyltransferase.
 
  
 0.882
galM
Aldose-1-epimerase (mutarotase); Converts alpha-aldose to the beta-anomer.
 
  
 0.778
galT
Galactose-1-phosphate uridylyltransferase.
 
  
 0.732
galE
UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
 
 0.705
galE-2
UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
 
 0.704
ptsH
Histidine-containing phosphocarrier protein of the PTS.
   
 
 0.570
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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