Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
adhBAlcohol dehydrogenase. (345 aa)    
Predicted Functional Partners:
czcD
Cation diffusion facilitator transporter - heavy metal transport.
  
 
 0.941
adh2
Probable alcohol dehydrogenase.
  
  
 0.898
nadC
Probable nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
   
  
 0.891
adhE
Alcohol-acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.845
spr1671
Conserved hypothetical protein; Similar to transcriptional regulator (MerR family).
       0.773
gapN
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.690
phnA
Required for expression of the phosphonate utilization phenotype in E. coli.
     
 0.528
prtA
Cell wall-associated serine proteinase precursor PrtA.
   
  
 0.519
atpH
Proton-translocating ATPase, F1 sector, delta-subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
      
 0.417
adhP
Alcohol dehydrogenase, propanol-preferring.
 
 
0.409
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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