Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
czcDCation diffusion facilitator transporter - heavy metal transport. (299 aa)    
Predicted Functional Partners:
adhB
Alcohol dehydrogenase.
  
 
 0.941
cadD
Confers low level cadmium resistance in Staphylococcus aureus.
  
   
 0.908
copY
COPAB ATPases metal-fist type repressor.
     
 0.904
adcR
Transcriptional repressor for Zn(2+)-responsive expression.
  
  
 0.894
psaA
ABC transporter substrate-binding protein - manganese transport; Part of an ATP-driven transport system; Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily.
  
  
 0.759
adcA
ABC transporter substrate-binding protein - Zinc (Zn2+) transport; Part of the ATP-driven transport system AdcABC for zinc. Required for transformability; Belongs to the bacterial solute-binding protein 9 family.
     
 0.735
ctpC
P-type ATPase - metal/cation transport.
  
  
 0.709
spr1673
Conserved hypothetical protein; Putative tetR-family transcriptional regulator.
     
 0.696
fcsK
Fucose kinase.
   
    0.692
prtA
Cell wall-associated serine proteinase precursor PrtA.
   
  
 0.605
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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