Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spr1679Hypothetical protein. (254 aa)    
Predicted Functional Partners:
spr1680
Hypothetical protein; Putative transcriptional regulator.
       0.841
proWX
ABC transporter membrane-spanning permease - choline transporter.
       0.833
proV
ABC transporter ATP-binding protein - choline transporter.
       0.829
spr1477
Conserved hypothetical protein.
 
    0.485
mip
Macrophage infectivity potentiator protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
  
     0.452
spr1468
Conserved hypothetical protein.
  
    0.451
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.