Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fatCABC transporter membrane-spanning permease - ferric iron transport; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (318 aa)    
Predicted Functional Partners:
fatD
ABC transporter membrane-spanning permease - ferric iron transport; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.999
fecE
ABC transporter ATP-binding protein - ferric iron transport.
 
  
 0.999
fatB
ABC transporter substrate-binding protein - ferric iron transport.
 
  
 0.997
amiC
ABC transporter membrane-spanning permease - oligopeptide transport; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
      
 0.889
ABC-NBD-15
ABC transporter ATP-binding protein - iron transport.
 
  
 0.774
ABC-MSP-9
ABC transporter membrane-spanning permease - iron transport; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
  
  
 0.754
ABC-MSP-10
ABC transporter membrane-spanning permease - iron transport; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
  
    0.698
codY
Transcriptional pleiotropic repressor; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
      
 0.600
spr0217
Conserved hypothetical protein; ACT domain containing protein.
      
 0.585
spr0500
Hypothetical protein.
      
 0.585
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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