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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trePPhosphotransferase system, trehalose-specific IIBC component. (705 aa)    
Predicted Functional Partners:
PTS-EII-12
Phosphotransferase system sugar-specific EII component.
 
 
0.999
ptsG
PTS glucose-specific enzyme IIABC component.
 
 
0.999
scrA
Phosphotransferase system enzyme II.
 
 
0.999
ptsH
Histidine-containing phosphocarrier protein of the PTS.
  
 0.984
dexS
Dextran glucosidase; Also highly similar to trehalose-6-phosphate hydrolase.
 
 
 0.984
fruA
Fructose specific-phosphotransferase system IIBC component.
 
  
 0.975
PTS-EII-15
Phosphotransferase system sugar-specific EII component.
 
 0.960
strH
Beta-N-acetyl-hexosaminidase precursor.
  
  
 0.953
spr1949
Hypothetical protein.
  
  
 0.950
spr0422
Hypothetical protein.
  
  
 0.942
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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