Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| flpA | lytA | spr0868 | spr1754 | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | Autolysin (N-acetylmuramoyl-L-alanine amidase). | 0.911 |
| flpA | nanA | spr0868 | spr1536 | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | Sialidase A precursor (neuraminidase A); Belongs to the glycosyl hydrolase 33 family. | 0.925 |
| flpA | pcpA | spr0868 | spr1945 | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | Choline-binding protein. | 0.735 |
| flpA | phtD | spr0868 | spr0907 | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | Pneumococcal histidine triad protein D precursor. | 0.596 |
| flpA | ply | spr0868 | spr1739 | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | Pneumolysin (sulfhydryl-activated toxin that lyses cholesterol containing membranes); Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity). | 0.951 |
| flpA | psaA | spr0868 | spr1494 | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | ABC transporter substrate-binding protein - manganese transport; Part of an ATP-driven transport system; Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily. | 0.925 |
| flpA | pspA | spr0868 | spr0121 | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | Surface protein pspA precursor. | 0.797 |
| flpA | pspC | spr0868 | spr1995 | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | Choline binding protein A. | 0.887 |
| flpA | spxB | spr0868 | spr0642 | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | Pyruvate oxidase; Belongs to the TPP enzyme family. | 0.619 |
| ldh | ply | spr1100 | spr1739 | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | Pneumolysin (sulfhydryl-activated toxin that lyses cholesterol containing membranes); Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity). | 0.920 |
| ldh | spxB | spr1100 | spr0642 | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | Pyruvate oxidase; Belongs to the TPP enzyme family. | 0.977 |
| lytA | flpA | spr1754 | spr0868 | Autolysin (N-acetylmuramoyl-L-alanine amidase). | Fibronectin-binding protein-like protein A; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. | 0.911 |
| lytA | nanA | spr1754 | spr1536 | Autolysin (N-acetylmuramoyl-L-alanine amidase). | Sialidase A precursor (neuraminidase A); Belongs to the glycosyl hydrolase 33 family. | 0.944 |
| lytA | pcpA | spr1754 | spr1945 | Autolysin (N-acetylmuramoyl-L-alanine amidase). | Choline-binding protein. | 0.527 |
| lytA | phtD | spr1754 | spr0907 | Autolysin (N-acetylmuramoyl-L-alanine amidase). | Pneumococcal histidine triad protein D precursor. | 0.459 |
| lytA | ply | spr1754 | spr1739 | Autolysin (N-acetylmuramoyl-L-alanine amidase). | Pneumolysin (sulfhydryl-activated toxin that lyses cholesterol containing membranes); Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity). | 0.949 |
| lytA | psaA | spr1754 | spr1494 | Autolysin (N-acetylmuramoyl-L-alanine amidase). | ABC transporter substrate-binding protein - manganese transport; Part of an ATP-driven transport system; Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily. | 0.949 |
| lytA | pspA | spr1754 | spr0121 | Autolysin (N-acetylmuramoyl-L-alanine amidase). | Surface protein pspA precursor. | 0.518 |
| lytA | pspC | spr1754 | spr1995 | Autolysin (N-acetylmuramoyl-L-alanine amidase). | Choline binding protein A. | 0.542 |
| lytA | spxB | spr1754 | spr0642 | Autolysin (N-acetylmuramoyl-L-alanine amidase). | Pyruvate oxidase; Belongs to the TPP enzyme family. | 0.860 |
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