Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
rpmH50S Ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (44 aa)    
Predicted Functional Partners:
rplU
50S Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
 
 0.987
rpmB
50S Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
 
 0.986
rpsT
30S Ribosomal protein subunit S20; Binds directly to 16S ribosomal RNA.
  
 
 0.982
rpsN
30S Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
  
 
 0.981
rpmJ
50S Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
  
 
 0.980
rpsP
30S Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
   
 
 0.979
rpsO
30S Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
   
 
 0.978
rpmF
50S Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
   
 
 0.978
rplX
50S Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
 
 0.977
rpmD
50S Ribosomal protein L30.
   
 
 0.977
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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