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pbp1b protein (Streptococcus pneumoniae R6) - STRING interaction network
"pbp1b" - Penicillin-binding protein 1B in Streptococcus pneumoniae R6
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pbp1bPenicillin-binding protein 1B (821 aa)    
Predicted Functional Partners:
pbpX
Penicillin-binding protein 2X; Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactams inactivate the PBPs by acylating an essential serine residue in the active site of these proteins (750 aa)
 
  0.994
dacA
D-alanyl-D-alanine carboxypeptidase (413 aa)
       
  0.992
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (352 aa)
 
 
  0.989
penA
Penicillin-binding protein 2B (685 aa)
 
  0.983
rodA
Rod shape-determining protein RodA (416 aa)
 
  0.934
ftsW
Cell division protein FtsW (409 aa)
 
  0.930
murN
Beta-lactam resistance factor (410 aa)
         
  0.929
pbpA
Penicillin-binding protein 1A; Cell wall formation (719 aa)
   
   
0.889
pbp2a
Penicillin-binding protein 2A (731 aa)
   
   
0.886
spr1908
Hypothetical protein (377 aa)
     
      0.871
Your Current Organism:
Streptococcus pneumoniae R6
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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