STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
malXABC transporter substrate-binding protein - maltose/maltodextrin; Binding protein for maltose and maltodextrin; involved in its cellular uptake. (423 aa)    
Predicted Functional Partners:
malC
ABC transporter membrane-spanning permease - maltose/maltodextrin; Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the substrate across the membrane.
 
 0.999
malD
ABC transporter membrane-spanning permease - maltose/maltodextrin; Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the substrate across the membrane.
 
 0.999
msmK
ABC transporter ATP-binding protein - multiple sugar transport; Belongs to the ABC transporter superfamily.
 
 0.997
malM
4-alpha-glucanotransferase (amylomaltase); Belongs to the disproportionating enzyme family.
  
  
 0.944
malA
MalA protein; Has a role in maltotetraose utilization.
 
  
 0.936
malR
Maltose operon transcriptional repressor; Transcriptional repressor of the maltosaccharide utilization operons malxCD and malMP.
 
  
 0.879
malP
Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
  
 0.840
msmF
ABC transporter membrane-spanning permease - multiple sugars.
  
 
 0.831
nplT
Neopullulanase; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.820
ABC-MSP-15
ABC transporter membrane-spanning permease - sugar transport.
  
 
 0.730
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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