Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
malDABC transporter membrane-spanning permease - maltose/maltodextrin; Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the substrate across the membrane. (287 aa)    
Predicted Functional Partners:
malX
ABC transporter substrate-binding protein - maltose/maltodextrin; Binding protein for maltose and maltodextrin; involved in its cellular uptake.
 
 0.999
malC
ABC transporter membrane-spanning permease - maltose/maltodextrin; Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the substrate across the membrane.
 
 0.999
msmK
ABC transporter ATP-binding protein - multiple sugar transport; Belongs to the ABC transporter superfamily.
 
 0.995
malA
MalA protein; Has a role in maltotetraose utilization.
 
  
 0.958
msmF
ABC transporter membrane-spanning permease - multiple sugars.
 
 
 0.945
ABC-MSP-17
ABC transporter membrane-spanning permease - sugar transport.
 
 
 0.918
ABC-MSP-15
ABC transporter membrane-spanning permease - sugar transport.
 
 
 0.914
ABC-MSP-19
ABC transporter membrane-spanning permease - sugar transporter.
 
 
 0.910
malR
Maltose operon transcriptional repressor; Transcriptional repressor of the maltosaccharide utilization operons malxCD and malMP.
 
  
 0.849
nplT
Neopullulanase; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.792
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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