STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arcBOrnithine transcarbamoylase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (338 aa)    
Predicted Functional Partners:
arcC
Carbamate kinase; Belongs to the carbamate kinase family.
 
 
 0.999
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.990
carB
Carbamoylphosphate synthase (ammonia), heavy subunit.
 
 
 0.983
carA
Carbamoylphosphate synthase (glutamine-hydrolysing) light subunit; Belongs to the CarA family.
 
 
 0.963
argH
Arginine succinate lyase.
 
  
 0.910
spr1956
Arginine deiminase, truncation.
 
  
 0.901
spr1955
Arginine deiminase, truncation.
 
  
 0.887
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.883
argR-2
Arginine repressor; Regulates arginine biosynthesis genes.
  
  
 0.870
argR
Arginine repressor; Regulates arginine biosynthesis genes.
  
  
 0.810
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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