Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
fucUFucose pathway protein, function unknown; Belongs to the RbsD / FucU family. (146 aa)    
Predicted Functional Partners:
fucA
L-fuculose phosphate aldolase.
  
  
 0.964
PTS-EII-20
Phosphotransferase system sugar-specific EII component.
  
    0.918
spr1965
Hypothetical protein.
 
  
 0.888
fcsK
Fucose kinase.
 
  
 0.886
PTS-EII-22
Phosphotransferase system sugar-specific EII component.
  
    0.866
PTS-EII-21
Phosphotransferase system sugar-specific EII component.
  
    0.852
PTS-EII-19
Phosphotransferase system sugar-specific EII component.
  
    0.780
spr1966
Conserved hypothetical protein.
  
    0.776
fucI
L-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose.
 
   
 0.769
fcsR
Regulator of fucose operon.
     
 0.708
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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