Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
adcAABC transporter substrate-binding protein - Zinc (Zn2+) transport; Part of the ATP-driven transport system AdcABC for zinc. Required for transformability; Belongs to the bacterial solute-binding protein 9 family. (501 aa)    
Predicted Functional Partners:
lmb
Lipoprotein; Belongs to the bacterial solute-binding protein 9 family.
 
 
0.999
phtD
Pneumococcal histidine triad protein D precursor.
  
  
 0.999
adcB
ABC transporter membrane-spanning permease - Zinc (Zn2+) transport.
 
 
 0.999
adcC
ABC transporter ATP-binding domain - Zinc (Zn2+) permease; Part of the ATP-driven transport system AdcABC for zinc. Required for transformability (By similarity).
 
 
 0.999
adcR
Transcriptional repressor for Zn(2+)-responsive expression.
  
  
 0.999
rpsN
30S Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
  
  
 0.963
phpA
Histidine Motif-Containing protein.
  
  
 0.960
psaC
ABC transporter membrane-spanning permease - manganese transport.
 
  
 0.860
spr0909
Hypothetical protein.
   
    0.831
psaB
ABC transporter ATP-binding protein - manganese transport.
 
   
 0.821
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
Server load: low (10%) [HD]