Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
adcCABC transporter ATP-binding domain - Zinc (Zn2+) permease; Part of the ATP-driven transport system AdcABC for zinc. Required for transformability (By similarity). (234 aa)    
Predicted Functional Partners:
lmb
Lipoprotein; Belongs to the bacterial solute-binding protein 9 family.
 
 
 0.999
phtD
Pneumococcal histidine triad protein D precursor.
   
  
 0.999
adcA
ABC transporter substrate-binding protein - Zinc (Zn2+) transport; Part of the ATP-driven transport system AdcABC for zinc. Required for transformability; Belongs to the bacterial solute-binding protein 9 family.
 
 
 0.999
adcB
ABC transporter membrane-spanning permease - Zinc (Zn2+) transport.
 
 0.999
adcR
Transcriptional repressor for Zn(2+)-responsive expression.
  
  
 0.999
psaB
ABC transporter ATP-binding protein - manganese transport.
  
  
 
0.919
stpA
ABC transporter ATP-binding protein - unknown substrate; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
  
0.917
ABC-NBP
ABC transporter ATP-binding protein - unknown substrate; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
  
  
0.910
ABC-NBD-4
ABC transporter ATP-binding protein - cobalt transport; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
   
 
 
0.900
ABC-NBD-9
ABC transporter ATP-binding protein - cobalt or other cation transport.
     
0.900
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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