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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rr06Response regulator. (217 aa)    
Predicted Functional Partners:
hk06
Histidine kinase.
 
 0.999
spr1996
Conserved hypothetical protein.
     
 0.973
hk08
Histidine kinase.
 
 0.960
rr09
Response regulator.
  
   
 0.940
hk02
Histidine kinase.
 
 0.906
vncS
VncS, histidine kinase.
 
 0.895
hk01
Histidine kinase.
 
 
 0.891
ciaH
Sensor protein CiaH histide kinase; Member of the two-component regulatory system CiaH/CiaR. Involved in early steps of competence regulation and in penicillin susceptibility. Probably phosphorylates CiaR.
 
 
 0.828
phoR
Histidine kinase.
 
 0.819
rr03
Response regulator.
  
 
 0.808
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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