STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucCsuccinyl-CoA synthetase subunit beta; Catalyzes the interconversion of succinyl-CoA and succinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)    
Predicted Functional Partners:
KJJ38026.1
succinate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
KJJ39696.1
2-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.992
sdhA
Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.991
KJJ39697.1
2-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.988
gltA
Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.984
KJJ37728.1
Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.978
KJJ37762.1
Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.970
KJJ39941.1
2-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.957
KJJ37731.1
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.954
KJJ38998.1
4-hydroxybutyrate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.947
Your Current Organism:
Aequorivita vladivostokensis
NCBI taxonomy Id: 171194
Other names: A. vladivostokensis, Aequorivita vladivostokensis (Nedashkovskaya et al. 2003) Hahnke et al. 2016, JCM 11732, KMM 3516, NBRC 16718, Vitellibacter vladivostokensis, Vitellibacter vladivostokensis Nedashkovskaya et al. 2003
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