STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KQM10423.1tRNA (guanine-N1)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)    
Predicted Functional Partners:
KQM10681.1
Similar to yeast Dim2p protein that is essential for 40S ribosomal subunit; structural studies show binding to 3' end of 16S rRNA in complex with archaeal IF2 alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.630
taw1
tRNA-modifying protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
  
 
 0.609
eif5a
Translation initiation factor IF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
     0.526
rpl4lp
50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
  
     0.513
KQM11032.1
Thermosome subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TCP-1 chaperonin family.
  
 
   0.487
eif2g
Translation initiation factor IF-2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
  
    0.474
psmA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
     0.461
pelA
Translation factor pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
  
     0.439
KQM10535.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.419
KQM10947.1
Shwachman#Bodian#Diamond syndrome protein family; SBDS; similar to eukaryotic proteins involved in RNA metabolism or binding; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.412
Your Current Organism:
Methanomassiliicoccales archaeon
NCBI taxonomy Id: 1713725
Other names: M. archaeon RumEn M2, Methanomassiliicoccales archaeon RumEn M2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.