STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OES44421.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (727 aa)    
Predicted Functional Partners:
OES44422.1
ATPase/protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
OES44420.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
0.993
OES44425.1
methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.985
OES44426.1
methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.954
OES44840.1
acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.933
OES46094.1
Ring-cleaving dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.931
OES46553.1
3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.871
OES44587.1
Carnitine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CoA-transferase III family.
    
 0.866
sucC
succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.864
sucD
succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.849
Your Current Organism:
Domibacillus iocasae
NCBI taxonomy Id: 1714016
Other names: CCTCC AB 2015183, D. iocasae, DSM 29979, Domibacillus iocasae Sun and Sun 2016, Domibacillus sp. S6, strain S6
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