STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPL46819.1peptidyl-tRNA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa)    
Predicted Functional Partners:
TruD
Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.661
KPL46820.1
tetrahydromethanopterin:alpha-L-glutamate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.637
KPL44905.1
Translation initiation factor IF-6; eIF-6; binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in eukaryotes; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.635
KPL47077.1
rRNA biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.623
KPL45481.1
DNA-directed RNA polymerase subunit D; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.584
KPL46818.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.576
PsmA
Proteasome subunit alpha; Cleaves peptide bonds; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.573
Fen
Endonuclease; FEN-1; Rad2; similar to eukaryotic enzymes; endonuclease that cleave the 5'overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'end of a downstream Okazaki fragment; as 5'endo-/exonuclease and 5'pseudo-Y-endonuclease activities; cleaves the junction between single and double-stranded regions of flap DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.540
KPL46697.1
tRNA (guanine-N2)-dimethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.534
rpl4lp
L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.531
Your Current Organism:
Methanosarcina flavescens
NCBI taxonomy Id: 1715806
Other names: DSM 100822, JCM 30921, M. flavescens, Methanosarcina flavescens Kern et al. 2016, Methanosarcina sp. E03.2, strain E03.2
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