STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPL46704.1Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)    
Predicted Functional Partners:
ThiD
Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
0.922
ThiL
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.919
ThiE
Thiamine-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.917
KPL45796.1
Hydroxyethylthiazole kinase; Catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.907
KPL46738.1
NTPase; THEP1; Aquifex aeolicus protein exhibits ATPase and GTPase activity; crystal structure shows RecA-like fold; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
RsgA-2
Ribosome biogenesis GTPase RsgA; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
KPL47104.1
Ribulose-1,5-biphosphate synthetase; In Methanocaldococcus jannaschii this enzyme is involved in conversion of 5-phospho-D-ribose-1-pyrophosphate to ribulose-1,5-bisphosphate using NAD as a cofactor; part of RubisCO pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.575
ThiC
Thiamine biosynthesis protein ThiC; Catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.575
ThiC-2
Phosphomethylpyrimidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.575
KPL46705.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.476
Your Current Organism:
Methanosarcina flavescens
NCBI taxonomy Id: 1715806
Other names: DSM 100822, JCM 30921, M. flavescens, Methanosarcina flavescens Kern et al. 2016, Methanosarcina sp. E03.2, strain E03.2
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