STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPL45603.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)    
Predicted Functional Partners:
KPL45602.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.818
tuf
Elongation factor 1-alpha; EF-1-alpha; EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-1-alpha-GDP leaves the ribosome and GDP/GTP exchange is promoted by EF-1-beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.814
KPL45874.1
serine--tRNA ligase; Functions to produce tRNACys in organisms that lack cysteinyl tRNA-synthetases; SepRS; uses modified amino acid; subclass IIc aaRS; attaches O-phosphoserine to tRNACys; the product of Mj1678 converts the Sep-tRNACys to Cys-tRNACys; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.633
KPL45601.1
RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.580
KPL46180.1
Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.567
leuS
leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; Derived by automated computational [...]
  
 
   0.566
RpoA2
DNA-directed RNA polymerase subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.519
KPL45359.1
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.493
KPL46959.1
GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.460
KPL46284.1
DNA polymerase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.452
Your Current Organism:
Methanosarcina flavescens
NCBI taxonomy Id: 1715806
Other names: DSM 100822, JCM 30921, M. flavescens, Methanosarcina flavescens Kern et al. 2016, Methanosarcina sp. E03.2, strain E03.2
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