STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FrhACoenzyme F420 hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)    
Predicted Functional Partners:
FrhG
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
FrhB
Coenzyme F420-reducing hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
FrhD
Coenzyme F420 hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.994
KPL45129.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.983
KPL45462.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.950
KPL45467.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.950
KPL46181.1
Disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.949
KPL44981.1
Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reduction of methenyl-tetrahydromethanopterin to methylene-tetrahydromethanopterin; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.925
KPL46383.1
F420H2 dehydrogenase; Similar to beta subunit of F420-reducing dehydrogenases; part of complex I; functions during electron transport; electron transport in archaea utilizes reoxidation of reduced coenzyme F420 coupled with the transport of protons across the cytoplasmic membrane and the hydrophobic electron acceptor methanophenazine; contains Fe-S centers and uses FAD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.920
Mer
Methylene-tetrahydromethanopterin reductase; Catalyzes the reduction of methylenetetrahydromethanopterin to methyltetrahydromethanopterin with the oxidation of coenzyme F420; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.917
Your Current Organism:
Methanosarcina flavescens
NCBI taxonomy Id: 1715806
Other names: DSM 100822, JCM 30921, M. flavescens, Methanosarcina flavescens Kern et al. 2016, Methanosarcina sp. E03.2, strain E03.2
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