STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPL44721.1ferredoxin-NADP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)    
Predicted Functional Partners:
GltA
Dihydropyrimidine dehydrogenase; NADH-dependent; catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
KPL47002.1
Dihydroorotate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.977
KPL46482.1
Dihydroorotase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.814
KPL46797.1
Orotate phosphoribosyltransferase; Catalyzes the formation of orotidine monophosphate from 5-phosphoribosyl-1-pyrophosphate and orotate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.789
PyrB
Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.786
KPL46168.1
Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.785
KPL44720.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
PyrF
Orotidine 5'-phosphate decarboxylase; Type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.772
KPL46167.1
Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.731
PylC
3-methylornithine--L-lysine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.731
Your Current Organism:
Methanosarcina flavescens
NCBI taxonomy Id: 1715806
Other names: DSM 100822, JCM 30921, M. flavescens, Methanosarcina flavescens Kern et al. 2016, Methanosarcina sp. E03.2, strain E03.2
Server load: low (16%) [HD]