STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polC_1DNA polymerase III PolC-type. (636 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.986
dnaX_1
DNA polymerase III subunit tau.
   
 0.984
dnaE
DNA polymerase III subunit alpha.
   
 0.972
OAH09572.1
Hypothetical protein.
    
 0.970
dnaX_2
DNA polymerase III subunit tau.
   
 0.930
dnaQ
DNA polymerase III subunit epsilon.
  
  
 
0.905
polC_2
DNA polymerase III PolC-type.
  
  
 
0.902
dnaE2
Error-prone DNA polymerase; Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
   
 0.786
OAH11792.1
Hypothetical protein.
   
 0.786
rpmD
50S ribosomal protein L30.
   
 0.743
Your Current Organism:
Streptomyces jeddahensis
NCBI taxonomy Id: 1716141
Other names: DSM 101878, LMG 29545, LMG:29545, NCCB 100603, S. jeddahensis, Streptomyces jeddahensis Rottig et al. 2017, Streptomyces sp. G25(2015), strain G25
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.