STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMK11782.1Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)    
Predicted Functional Partners:
AMK10485.1
HemD protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.934
AMK11017.1
Precorrin-2 C(20)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.
    
 0.923
AMK12304.1
Precorrin-2 C(20)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.
    
 0.923
hemL
Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.922
AMK12301.1
Cobalt chelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family.
    
 0.918
AMK12305.1
Cobalt chelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family.
    
 0.918
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
   
 0.884
cysC
Adenylyltransferase; Catalyzes the synthesis of activated sulfate.
 
  
 0.881
cbiF
Catalyzes the formation of cobalt-precorrin-5 from cobalt-precorrin-4; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.833
Your Current Organism:
Pseudodesulfovibrio indicus
NCBI taxonomy Id: 1716143
Other names: DSM 101483, Desulfovibrio indicus, Desulfovibrio sp. J2, MCCC 1A01867, P. indicus, Pseudodesulfovibrio indicus Cao et al. 2016, strain J2
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